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Arthritis Therapy

An adequate therapy of arthritis depends on the extend of the degenerative or traumatic cartilage damage and can be non-operative, like physiotherapy, orthotics, drugs, local injections, radiosynoviorthesis or surgical, by means of arthroscopy up to joint replacement surgery. Attempts to surgically (abrasion surgery) promote the regeneration of cartilage have – so far – only affected growth of inferior fibrous cartilage tissue, but not the growth of a functional, intact hyaline cartilage tissue.  Based on this background new therapy concepts are emerging that aim to heal cartilage effects by implementing the physiological healing characteristics of the bodies own cells or proteins.

Aside of the new therapies with Autologous Chondrocyte Transplantation (ACT) as well as the Autologous Conditioned Plasma (ACP) or Autologous Conditioned Serum (Protein therapy, ACS) a new treatment for tissue engineering of bone, cartilage and soft tissue has emerged: the use of ACBM – Autologous Concentrated Bone Marrow. The repair cells found in ACBM have a distinguished capacity to proliferate (multiply) and differentiate (change into various body cells).

A disadvantage of the Autologous Chondrocyte Transplantation (ACT) is that it requires two surgeries, in the course of the first one healthy cartilage is extracted and surgery related injury could occur. This could lead to the beginning of a degenerative process in a healthy area of the joint and can lead to added pain and further impairment.

Autologous Spongiosa/Bone Marrow transplantation is a long known surgical technique in orthopedics; during this procedure cancellous bone is extracted at a donor site (in the same patient) in order to stimulate healing of bone-cartilage defects.

Macro technique for the homologous transplantation of bone marrow

Cancellous bone spongiosa is commonly used for stabilization and as carrier substance, for instance in spinal fusion surgery or for joint replacement surgery, reinforcement of the jawbone for implants and in reconstructive surgery for filling and modulation of various bone areas. 

Micro technique for the homologous transplantation of bone marrow

The Pridi-drilling, the micro-fracture and in particular the abrasion-arthroplastic are surgical techniques which have been applied for many years. During the procedure the surgeons drill away or puncture the corticalis of the joint cartilage up to the bone marrow space of the bone, in order to promote a bleeding of bone marrow cells (on average 0,02 % stem cells) into the joint. This operative technique aims to facilitate the growth of new cartilage.

The disadvantages of the above mentioned surgical techniques mentioned are the possible side effects / risks of surgery as well as possible growth of scar tissue in the operated area (fibrosis).

Biological effect of autogenous spongiosa / bone marrow application

The healing process of the autogenous spongiosa application is affected without a doubt only by the living cell organisms – also stem cells - located within the spongiosa, in the so called bone marrow.

Our new therapy concepts enable us to use the active, organic parts of the autogenous spongiosa (bone marrow) in minimally invasive approaches. The collected bone marrow concentrate and/or the autologous proteins/ plasma can be implemented by means of thin cannulae up to the degenerative cartilage/bone/joint defect while NOT causing large surgical defects, with all the advantages of minimally invasive techniques. Furthermore, we can combine these minimally invasive therapies with gold standard therapies (for instance arthroscopic surgery) in order to optimize the therapy outcome. 

 

 

 

 

 

Therapy Spectrum 

 

ACS - Autologous Conditioned Serum

 

ACP - Autologous Conditioned Plasma

 

ACBM - Autologous Concentrated Bone Marrow

 

Hyaluronic Acid

 

Alternative Therapies 

 

Homeopathy 

 

DNA Analysis